Ms4a2 Polyclonal Antibody for Mouse(Mus musculus) | EIAab.comMs4a2 Polyclonal Antibody for Mouse(Mus musculus)

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Ms4a2 (Gene name),

High affinity immunoglobulin epsilon receptor subunit beta (Protein name ), FCERB_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Ms4a2(Fce1b;Fcer1b;Ms4a1);

Protein name:

High affinity immunoglobulin epsilon receptor subunit beta(FcERI);

Alternative:

IgE Fc receptor subunit beta;Fc epsilon receptor I beta-chain;Membrane-spanning 4-domains subfamily A member 2;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Tetramer of an alpha chain, a beta chain, and two disulfide linked gamma chains. Binds LILRB1. Interacts with FGR (By similarity). Interacts with FGR and FES/FPS.

Function:

High affinity receptor that binds to the Fc region of immunoglobulins epsilon. Aggregation of FCER1 by multivalent antigens is required for the full mast cell response, including the release of preformed mediators (such as histamine) by degranulation and de novo production of lipid mediators and cytokines. Also mediates the secretion of important lymphokines. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators responsible for the manifestations of allergy.

Subcellular Location:

Membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

235

Sequence:

50:

100:

150:

200:

235:

SKKVPDDRLY | EELNVYSPIY | SELEDKGETS | SPVDS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

10090.ENSMUSP00000025583

String:

P20490

UniGene:

Mm.329735

Pfam:

PF04103

KEGG:

mmu:14126

Uniprot:

P20490

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ELISA Kit for Mouse FcERI

Cat.:

E1891r

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Manual:

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MSDS:

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Packing:

96T

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ELISA Kit for Mouse FcERI

Cat.:

E1891m

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MSDS:

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Packing:

96T

ELISA Kit for Mouse FcERI

Cat.:

E1891h

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MSDS:

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Packing:

96T

CLIA Kit for Mouse FcERI

Cat.:

U1891m

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MSDS:

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Packing:

96T

CLIA Kit for Mouse FcERI

Cat.:

U1891h

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MSDS:

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Packing:

96T

CLIA Kit for Mouse FcERI

Cat.:

U1891r

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse FcERI

Cat.:

P1891Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse FcERI

Cat.:

P1891Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse FcERI

Cat.:

P1891Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse FcERI

Protein for Mouse FcERI

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Complete structure of the mouse mast cell receptor for IgE (Fc epsilon RI) and surface expression of chimeric receptors (rat-mouse-human) on transfected cells."
Ra C. , Jouvin M.H.E. , Kinet J.-P.
J. Biol. Chem.264:15323-15327(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"The genomic structure of the allergy associated Fc receptor beta subunit and its high content of SINEs."
Hiraoka S. , Watanabe M. , Takagaki Y. , Fujita-Suzuki K. , Shinohara N. , Okumura K. , Ra C.
Submitted (1999-10) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
strain: 129.
3.

"Positive and negative regulation of mast cell activation by Lyn via the FcepsilonRI."
Xiao W. , Nishimoto H. , Hong H. , Kitaura J. , Nunomura S. , Maeda-Yamamoto M. , Kawakami Y. , Lowell C.A. , Ra C. , Kawakami T.
J. Immunol.175:6885-6892(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION;INTERACTION WITH LYN
4.

"Quantitative time-resolved phosphoproteomic analysis of mast cell signaling."
Cao L. , Yu K. , Banh C. , Nguyen V. , Ritz A. , Raphael B.J. , Kawakami Y. , Kawakami T. , Salomon A.R.
J. Immunol.179:5864-5876(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-210; TYR-216; SER-217 AND TYR-220;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Mast cell.
5.

"Contributions of F-BAR and SH2 domains of Fes protein tyrosine kinase for coupling to the FcepsilonRI pathway in mast cells."
McPherson V.A. , Everingham S. , Karisch R. , Smith J.A. , Udell C.M. , Zheng J. , Jia Z. , Craig A.W.
Mol. Cell. Biol.29:389-401(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH FES/FPS

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